Testicular
Mesothelioma - Symptoms, Development, Diagnosis & Treatment
Options for Testicular Mesothelioma
(August 1st, 2008)
Testicular
mesothelioma is when malignant tumors invade the tunica vaginalis;
a membranous lining that surrounds, protects & insulates the
testicles. Since the testicles are the reproductive organs of the
human body, it can be very dangerous if they are damaged by cancerous
tumors. The tunica vaginalis is composed of mesothelial cells, which
are cells that line the body's serous cavities and internal organs
and provide protective, non-adhesive surfaces. Mesothelial cells
also help in transporting fluids and cells across the serous cavities.
The image on the left is of the tunica vaginalis composed of 2 layers;
parietal (outer) layer and visceral (inner) layer.
Testicular mesothelioma is the rarest form of mesothelioma lung
cancer out there with only 100 cases diagnosed this year. Since
it is extremely rare, doctors do not know exactly how it is caused.
Scientists suggest 2 possible ways how testicular mesothelioma can
develop; 1) patients with testicular mesothelioma have primary tumorous
cells in the peritoneal membrane, while developing secondary tumors
in one or both of the testicles and 2) patients develop primary
tumors in the testicles. When testicular mesothelioma develops as
a secondary tumor, it is quite possible that the source of the Cancer
is a peritoneal tumor that spreads (metastasizes) to other organs
and areas of the body, including the lymph nodes. Scientists still
however do not know how a primary tumor can develop directly in
the testicles.
How do cells become cancerous? Once a primary tumor forms in the
testicle or in the peritoneal membrane, cells go out of control
and can no longer control their growth. They divide without restraint
which then causes the tunica vaginalis to thicken and grow. This
eventually leads to the formation of tumors.
Symptoms of Testicular Mesothelioma
Unlike peritoneal, pleural & pericardial mesothelioma where
there is a list of common symptoms, there are no defined symptoms
for testicular mesothelioma. One of the most distinguished symptom
of testicular mesothelioma is appearance of testicular lumps in
the testicles. This is the only recognized sign by which doctors
can diagnose testicular mesothelioma. Testicular lumps are usually
found when a patient undergoes surgery or a biopsy.
Treatment Options for Testicular Mesothelioma
The most common treatment option available for testicular mesothelioma
is the removal of the testicles, or a portion of it. If the cancer
has advanced very high, it may be necessary to remove the entire
testicles. Other treatment options available are Chemotherapy or
radiation therapy. Radiation therapy will attempt to kill any cancerous
cells in the testicles via the help of a high beam razor that directly
targets tumorous cells. Following treatment options, testicular
mesothelioma has the habit of recurring after a few years. This
is because it is classified as a "clinically aggressive type
of cancer" and can spread & grow very fast.
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